Aiming at the disadvantages of large volume and high cost of traditional spectrum acquisition equipment, a driving and acquisition circuit of infrared spectrum sensor controlled by FPGA is designed based on MEMS-FPI spectrum sensor C14272 developed by Hamamatsu. The circuit includes voltage driving module of the tunable filter, spectrum and temperature signal acquisition module, USB transmission module and so on. The test results show that the spectrum of the C + L band ASE light source obtained by the circuit is similar to the simulation spectrum, which realizes the driving of the spectrum sensor and the collection of spectrum data. The wavelength detection range of the circuit is 1350-1650nm and the full band spectral resolution is less than 18nm. The design is compact in structure and low in cost, which is helpful in specific fields such as qualitative detection of material composition.