Aiming at the problem of system performance degradation caused by delay and packet loss in the network control system, a new delay and packet loss compensation method is proposed. First, establish a time-delayed network control system space model, transform the time-delay network control system into a non-delay system through linear conversion, and use autoregressive algorithm to predict the time delay online, and then give an improved reaching law The sliding mode controller compensates for the delay, and uses a zero-order holder with logic judgment function to deal with the packet loss problem. This method has better real-time performance in predicting time delay, and better system stability and robustness in dealing with packet loss problems. The simulation results on the Truetime platform show that this method has a better compensation effect on network delay and packet loss.