Aiming at the security problem of pseudo-random number in cryptographic applications, based on the characteristics of superlattice physical entropy source, this paper analyzes the advantages of stimulated chaos as entropy source, and proposes for the first time that the stimulated chaos oscillation of superlattice is used as entropy source of true random number generator, 12 bit ADC is used to realize digital sampling of stimulated chaos signal of superlattice, and FPGA is used as post-processing unit, A true random, high-performance and high-speed superlattice random number generator is designed and implemented. The real-time generation rate of random number is up to 300mbps. The performance of the superlattice random number generator can pass the standard (NIST sp 800-22) provided by the National Bureau of standards. The results show that the superlattice random number in this paper has good randomness.