Early and accurate detection of cardiovascular disease is of significant importance to reduce the mortality caused by it. In view of the digital and synchronous combined detection technology bottlenecks in the common auscultation and ECG detection methods used in the early detection of cardiovascular diseases, a highly sensitive heart sound probe based on the MEMS vector hydrophone chip was developed and integrated a 5-road heart sounds and standard 12-lead ECG simultaneous acquisition instrument system. The test results show that the developed heart sound sensor probe has a signal-to-noise ratio of 40dB, which is better than the 3M stethoscope; and the QRS wave ECG signal collected by the system is synchronized with the characteristic peaks of the S1 and S2 heart sound signals, and the waveform characteristics are accurate and clear. The test has realized the digital detection of heart sounds and the intuitive identification of abnormal characteristics of the disease. In addition, the system is optimized to have intelligent diagnosis capabilities. Therefore, a cloud server and database have also been built, and an intelligent diagnosis algorithm for heart sounds has been designed and developed. Through testing on the collected clinical case, the results show that the accuracy of the five-category heart sound intelligent recognition is over 90%. Therefore, the detection system has important technical value and clinical guiding significance for assisting physicians in the early digital detection and joint diagnosis of cardiovascular diseases.