In recent years, more and more multi-circuit cable lines of different voltage levels are laid underground of the cities, multi-circuit can cause the problems of circulation loss on cable metal sheath become severe, the different voltage levels of the cable lines are mixed laid, which have a greater impact on circulating current. Based on the principle of electromagnetic induction, calculating the induced voltage of 10, 110 kV single core cables in this paper, both of sheaths with applied cross-bonding connection. Circulating current matrix equation is figured out by the impedance model, and finally get the result of circulating current on the metal sheath of different voltage cable lines and the interdependent of each other. The results show that mixed-laying will lead the 10,110 kV line circulating current increase and decrease; 10, 110 kV line’s circulating current will increase with the increasing of space between different phases, but interaction between them is different,10 kV line circulating current increased by 48.99% when 110 kV line phase spacing increased 200 mm,10 kV line phase spacing increased 200 mm, the 110 kV line circulating current almost did not change; the arrange of three segments length of cable on cross-bonding unit will affect their own circulating current, but does not impact the circuit which next to; the varies of load current influence circulating current greatly; The greater the vertical distance between the 10,110 kV line, the smaller the circulating current is; the circulating current is the largest as the phase sequence is BAC-CAB(10~110 kV), the smallest circulating current appears when the phase sequence is CBA-ACB(10~110 kV). The results above will have good reference for cable route planning and design.