As an important industrial site of natural gas transmission and distribution system, it has become particularly important for LNG gas station to ensure safe operation and reduce potential safety hazards. The article takes the actual project of a liquefied gas station as the background. In order to improve the safety performance of small and medium-sized LNG gas station control system, a cost-effective intelligent monitoring system was designed. It implements a human-computer interaction interface and real-time data acquisition monitoring alarming and interlocking functions in order to meet the production monitoring needs of LNG gas stations based on FIX configuration software and SHCAN fieldbus. The system test results show that the real-time display of the completed data can be refreshed within 300 ms, several years’historical data can be recorded and it can realize alarm management. The operation results that the monitoring system designed by this project is correct and effective.