In view of the problem that the conventional single isolation ship rolling mode in the shipborne TT&C system cannot meet the requirements of TT&C under complex sea conditions, this paper proposes to adopt multi-combination isolation ship rolling technology for TT&C. This paper analyzes the system principle of isolation ship rolling mode of shipboard measurement and control system, and puts forward the method of selecting appropriate combination of isolation ship rolling according to different environment to realize stable tracking target and improve the isolation degree of ship rolling. Mainly introduced the principle of swinging ship various isolation technology and the similarities and differences, using the test data, this paper compares and analyzes the results for convenient combined isolation in different sea environment, the application of the results show that through the combined isolation more accurate selection, can better and more stable tracking target, to show more swinging ship combined isolation technology for system stability tracking and essence of determine the rail has important significance.